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Scientia et Labore · Through Knowledge and Work

One front door to health research at Wits.

Find, fund, govern and measure Faculty research capability — from equipment and datasets to expertise, grants, outputs and compliance, all in one connected place.

Search the hub Equipment first
Smart match by technique & availability 142 instruments
Sequencing — free today Confocal microscopy Flow cytometry −80°C biobank space
Modes marked are federated — staff and publications come live from the Wits Research Visibility Platform; the hub links to them, it doesn't duplicate them.
5Schools federated
1,741ORCID-verified profiles
2,300+Datasets & outputs
140+Instruments & facilities
GovernedPOPIA-aligned by design
Demo version. Interface, workflows and user journeys are shown using illustrative data. Final figures will be validated with Faculty data owners before launch.
How the hub is structured

Three experiences, one connected hub

The same research ecosystem, presented three ways depending on who you are and what you're doing — a public shop window, a discovery workspace, and an authenticated operational layer.

Public discoveryNo login · the shop window Open

Markets the Faculty's research capability to the world. Answers: what research and facilities exist here?

  • Faculty overview & research themes
  • Featured facilities & datasets
  • Schools, centres & departments
  • Latest publications & success stories
  • Public equipment catalogue
Anyone can browse →
Search workspaceThe discovery interface Discover

A search drops you into a discovery workspace — closer to OpenAlex or Dimensions than a homepage.

  • Unified results: equipment, data, people
  • Publications, projects, funding, centres
  • Filters and rich previews
  • AI semantic search across the graph
  • The search becomes the workspace
Search-driven →
Operational workspaceAfter Wits sign-in Secure

Authentication unlocks the personalised, role-aware tools. These are operational, not discovery.

  • Bookings, deposits & approvals
  • Grant tracking & reporting
  • Supervision & finance
  • Facility management & recharge
  • Role-based dashboards (below)
Wits SSO required →

What this is

A connected access layer that sits on the Faculty website and links existing systems, people, equipment, datasets, grants and support workflows — one front door to research capability across FHS.

What this is not

Not another standalone website, and not a replacement for the Visibility Platform, HREC portal or finance systems. It federates to those systems of record rather than duplicating them.

A phased rollout

Ambitious in vision, controlled in delivery

The full ecosystem is shown here to convey the destination. Delivery is staged — discovery first, then operations, then the automation layer.

Phase 1 · Discovery

Faculty Research Discovery Hub

The public shop window and search — no authentication required.

  • Equipment search & public catalogue
  • Unit & researcher profiles
  • Public landing pages & support directory
Phase 2 · Operations

Operational workflows

Authenticated tools via Wits SSO. Requires integration with institutional systems.

  • Equipment booking & data deposit
  • Grant tracker & role-based dashboards
  • Approvals & reporting workflows
Phase 3 · AI & automation

AI & automation layer

The enabling layer, added once the connected data is flowing.

  • Funding matching & recommendations
  • AI summaries, alerts & metadata
  • Automated cross-linking across the graph
Why this matters

A research operations hub, not a directory

The value is visibility, coordination, access and accountability. AI sits underneath, improving search, matching and summaries — it isn't the point of it.

Access

Shared equipment found and booked in a click, with training and cost recovery built in.

Efficiency

Utilisation visible, bottlenecks forecast, duplicate purchases avoided across the faculty.

Governance

POPIA-aligned access, ethics linkage and audit trails wherever sensitive data moves.

Decision support

Leadership sees ROI, pipeline and capacity across all schools and cores in one place.

Underneath: one connected knowledge graph

Every entity links to every other. That connected graph is what makes search, dashboards, recommendations, AI and reporting feel intelligent rather than merely searchable.

Researcher Department School Project Grant Equipment Dataset Publication Student Centre Theme

Got data, an instrument, or a proposal in the works?

Deposit a dataset Start a pre-award draft
Home/Equipment & core facilities
Equipment & core facilities · Full operations module

A complete core-facility system, not just a list

Browse, book, train, track and recharge across every shared instrument in the faculty — scheduled-vs-actual usage, cost recovery against grants, and access gated on training. The full core-facility toolset, hosted locally under institutional control.

Smart match by technique
Illumina NovaSeq 6000
Genomics & Sequencing Core · Wits FHS, Parktown · Custodian: Dr N. Mahlangu
R / sample (internal) Training required Add-on charges SOPs attached
Free now
Zeiss LSM 980 Confocal
Imaging & Microscopy Core · Custodian: Dr P. Khumalo · Interlock-controlled
R / hour (internal) Certification required Kiosk usage tracking
Booked to Thu 14:00
−80°C Biobank Array (Bay 3)
Biobank & Cold Storage · Chain-of-custody logged · Consent-linked to deposits
R / rack / month Barcode inventory POPIA consent gate
Capacity free
Mass Spec — Q Exactive HF-X
Mass Spectrometry Core · Custodian: Dr T. Naidoo
R / run + consumables Service request workflow Cost-tracked to grant
Calibration · back Mon
Scheduling & calendars

Min/max reservation windows, time-steps, no-show release, walk-up bookings and waitlists per instrument.

Kiosk & interlock tracking

Scheduled-vs-actual logged time at a kiosk station; optional interlock gates power/software to authorised users.

Recharge & billing

Internal/external rates, add-on consumable charges, cost-tracking against project IDs, invoices to the finance system.

Access & training control

Bookings gated on completed training and valid certification; sensitive/containment equipment restricted by role.

Inventory & samples

Barcoded inventory, sample location, container/consumable management and chain-of-custody for biobank holdings.

Utilisation reporting

Usage, downtime, recharge capture and ROI per instrument and per core — exportable for the deputy dean's reviews.

Publication tracker

Outputs that used a facility link back to it automatically — evidence of each core's contribution to the faculty's research.

AI demand forecasting

Predicts bottlenecks, flags under-used assets and suggests scheduling that lifts utilisation across the faculty's shared instruments.

Covers the core-facility capabilities the faculty needs

Searchable equipment, booking, training requirements, access rules, usage reporting and cost recovery — with these functions linked to faculty profiles, grants, datasets and research outputs, hosted locally under institutional control.

Core capabilitiesScheduling · Kiosk · Recharge · Access · Inventory · Reporting
Connected & governedLinked to grants & data · Local hosting · POPIA-aligned
Home/Equipment/Illumina NovaSeq 6000

Illumina NovaSeq 6000

Genomics & Sequencing Core · Wits FHS, Parktown
Free now Training required Custodian: Dr N. Mahlangu
R—per sample (int.)
81%Utilisation
47Projects served
128Datasets generated
2031Service to

Overview

High-throughput short-read sequencing platform for whole-genome, exome and targeted panels. Supports large-scale population genomics and pathogen surveillance across the Faculty. Operated by the Genomics & Sequencing Core under custodian supervision; certification and a valid reservation are required before use.

Booking & access rules

Reservation windowMin 4 hours · max 3 days · no-show release after 30 min
Training gateCertification required · 2 sessions pending approval
RechargeInternal rate per sample · external on request · add-on consumables

Connected through the hub auto-linked

Linked grantsEVAH · TB genomic surveillance
3 →
Datasets generatedSequencing output deposited to the repository
128 →
PublicationsOutputs citing this instrument (Visibility Platform)
41 →

Availability

TodayFree
This week3 slots
Next bookingWed 09:00

Specifications

PlatformNovaSeq 6000
Outputup to 6 Tb
Read length2×150 bp

Maintenance

Last serviceApr 2026
CalibrationCurrent
Home/Data repository
Data repository · Governed by design

Sensitive health data, shared safely

Persistent IDs minted locally for sovereignty, rich metadata for reuse, and a controlled-access workflow that checks ethics before anything is released.

Recent deposits FAIR-scored on deposit
Gauteng PHC waiting-time cohort, 2025ark:/afhied/ds-7741 · HREC M2401-77 ✓
Open
TB genomic surveillance — isolate panelark:/afhied/ds-7720 · controlled access
Restricted
Maternal NCD linkage dataset (pre-pub)ark:/afhied/ds-7702 · embargo to 2026-09
Embargoed
HIV treatment continuity, Stanza Bopapeark:/afhied/ds-7688 · HREC M2312-15 ✓
Open
AI flagged: possible identifiers in 2 columnsDe-identification suggested before release · awaiting custodian sign-off
  • Ethics, linked not stored

    Each record carries its HREC reference, status and expiry, deep-linked to the Wits HREC portal ↗. Release is gated on a valid approval.

  • Local persistent IDs

    ARK or self-hosted Handle PIDs by default for data sovereignty — with DOIs registered on demand for datasets headed into the literature.

  • POPIA-aligned access control

    Data-sovereignty rules and consent scope checked at the point of release; controlled-access requests routed, approved and audited with a full trail.

  • Metadata that travels

    Standards-aligned descriptions keep datasets harvestable by global aggregators without surrendering control of the data itself.

Home/People & expertise
People & expertise · federated from the Visibility Platform

Find researchers and staff

Profiles are drawn live from the Wits Research Visibility Platform. The hub adds operational context — roles, group membership, equipment custodianship — and gives professional staff a profile too.

Member category All Academic staff Professional staff Postgraduate Postdoctoral Honorary & emeritus
AM
Prof. Aletta MillenAssistant Dean: Research
CardiovascularNeuroinflammation
PK
Dr P. KhumaloFacility Manager · Imaging Core
ConfocalOperational profile
NM
Dr N. MahlanguCustodian · Genomics Core
SequencingGenomics
KO
Dr Kennedy OtwombePI · biostatistics
BiostatisticsTrials
RD
Research Dev. OfficerProfessional staff · grants
Operational profilePre-award
+
1,741 profilesBrowse the full directory
Federated · Visibility Platform
Home/People/Prof. Aletta Millen
AM

Prof. Aletta Millen

Assistant Dean: Research · Faculty of Health Sciences
ORCID-verified Bio & metrics federated Cardiovascular · Neuroinflammation
75Publications
14H-index
48Journals
2Institutions
2007–18Active years

Research summary AI-generated

Aletta Millen is a cardiovascular and neuroinflammation researcher whose work centres on the systemic consequences of chronic inflammation. Using well-established rodent models, her research explores how inflammatory pathways driven by cytokines such as TNF-α and IL-6 contribute to cardiac remodeling, ventricular dysfunction, and heart failure phenotypes. Her studies integrate molecular biology, echocardiography, and mass spectrometry imaging to elucidate mechanisms linking immune activation to structural and functional cardiac changes.

A major focus of her scholarship is the role of inflammasome activation, cytokine blockade, and microRNA regulation in inflammation-induced cardiac injury. Her work has clarified how TNF-α mediates early systolic dysfunction and myosin isoform shifts, while IL-6 signalling shows complex, context-dependent effects on lipid metabolism, fibrosis, and ventricular performance — contributing to a nuanced understanding of biologic therapies in autoimmune and hypertensive disease models.

Millen has also advanced research on neuroinflammation and mood disorders, examining HPA axis dysregulation, monoamine alterations, and neurotrophic signalling in inflammatory states. Her contributions extend to translational perspectives on depression treatment in African contexts, including the therapeutic promise of ketamine. Collectively, her work bridges cardiovascular pharmacology, immunology, and neurobiology.

Expertise & methods

Cardiovascular pharmacologyNeuroinflammationCardiac remodelingEchocardiographyMass spectrometry imagingmicroRNA regulationAI-tagged expertise

Latest publications

Predictive diagnostic models for newly diagnosed diabetes mellitus in moderate to severe COVID-19The role of TyG Index, BMI, and inflammatory markers
Decreased blood pressure with acute administration of quercetin in L-NAME-induced hypertensive ratsCardiovascular pharmacology
1 / 4 →

Connected through the hub auto-linked

Publications & outputsFederated live from the Visibility Platform
75 →
Facilities usedImaging Core · Mass Spectrometry Core
2 →
Postgraduate supervisionTracked through the hub
Suggested for youAI-matched to this profile
All Funding Training Collaborators Publications Equipment Data
Funding · SA-MRCSelf-Initiated Research Grant — CardiovascularMatches cardiovascular & inflammation focus · closes in 12 days
91% fit
Training · UlwaziAdvanced echocardiography analysisBuilds on her imaging methods · self-paced
88% fit
CollaboratorDr T. Naidoo — immunologyComplementary cytokine expertise · 3 shared themes
86% fit
New publicationIL-6 signalling in cardiac fibrosis: a 2026 reviewRelevant to her IL-6 / fibrosis work
79% fit
EquipmentQ Exactive HF-X mass spectrometerFor her mass-spec imaging workflows · free this week
77% fit
DatasetRodent cardiac inflammation panel, 2025Reusable · matches her model systems
74% fit

Role

PositionAssistant Dean: Research
FacultyHealth Sciences

Bibliometrics

Publications75
H-index14
Publishing journals48
Institutions2

Identifiers

ORCIDVerified
SourceVisibility Platform
Home/Units
Home/Units/School of Public Health
PH

School of Public Health

Faculty of Health Sciences · organisational profile
EpidemiologyHealth systemsHIV / TBNCDs
142Researchers
R20M+Active grants
8Facilities
214Postgrads
2,300+Outputs

Overview

One of five schools in the Faculty of Health Sciences, spanning epidemiology, health systems, health policy and biostatistics. The School anchors several flagship cross-cutting programmes and operates a portfolio of core facilities shared across the Faculty.

Research themes

HIV / TBHealth systemsNCDsEpidemiologyHealth policyGenomics

Connected through the hub live

Leadership & researchersFederated from the Visibility Platform
142 →
Equipment & facilitiesGenomics, Imaging, Biobank, Mass spec …
8 →
Grants & projectsR20M+ active across the portfolio
11 →
Postgraduate activity214 candidates · supervision tracked
214 →
Suggested for this unitAI-matched to its research profile
All Funding Training Collaborators Publications Equipment Data
Funding · WellcomeDiscovery Research AwardsStrong fit for health systems + AI · 6 eligible PIs
94% fit
Funding · GatesGrand Challenges — TB DiagnosticsMatches TB genomic-surveillance programme
88% fit
Training · UlwaziStepped-wedge & cluster trialsHigh demand across the school's postgrads
90% fit
Collaborator unitSydney Brenner InstituteGenomics capacity complements HIV/TB themes
85% fit
New publications12 recent outputs in health systemsTrending in the school's themes this quarter
80% fit
EquipmentNovaSeq 6000 — Genomics CoreUnder-used capacity for surveillance work
78% fit
DatasetGauteng PHC waiting-time cohortReusable open data for health-systems research
75% fit

Performance

Output trend↑ 12%
Facility ROIR2.4M
Grant pipeline6 in pre-award

Template note

The same profile template serves a Department, Research Centre, Institute (e.g. Sydney Brenner Institute), Programme, Unit, Laboratory or Core Facility.

Home/Funding & pre-award
Funding tools, trackers & pre-award support

From opportunity to award, tracked end-to-end

Discovery, portfolio tracking and pre- to post-award in one workspace — with an AI matcher that scores every open call against the faculty's expertise and a clean handoff to the Wits Research Office for submission.

3 high-fit calls close within 30 days. The AI matcher flagged them against active faculty expertise and open capacity. Manage alerts →
AI funding matcher 28 open calls · scored by fit
All High fit Closing soon Eligible
Wellcome Trust 94% fit

Discovery Research Awards

Up to £3MDuration 5–8 yrsResponse-mode
Matches faculty strength in health systems + AI; 6 eligible PIs and prior Wellcome track record.
Closes in 22 days
SA-MRC 91% fit

Self-Initiated Research Grant — Cardiovascular

Up to R1.5MDuration 3 yrsNational
Aligns to cardiovascular & inflammation research; strong fit for Prof. Millen's group.
Closes in 12 days
Gates Foundation 82% fit

Grand Challenges — TB Diagnostics

Up to $1MDuration 2 yrsGlobal
Overlaps TB genomic-surveillance work; 4 aligned researchers, moderate scope match.
Closes in 5 weeks
NRF 76% fit

Thuthuka Funding Instrument

Up to R350KDuration 3 yrsEarly-career
Best fit for emerging researchers; 11 eligible early-career staff across the faculty.
Closes in 8 weeks

Grant portfolio & tracking

Every active award with spend, milestones and AI monitoring — cross-linked to the people, data and equipment it touches.

Grant tracker — active portfolio
Active Pipeline Closed
AI-enabled clinical decision support (EVAH)
Wellcome / Gates / Novo Nordisk via J-PAL + APHRC · Kennedy Otwombe (PI)
$994,545
Spend: 38% drawnYr 1 of 3
Milestone 2 due 30 Jul AI: spend on track
CB-SITS Africa capacity strengthening
Carnegie Corporation of New York
$181,000
Spend: 93% drawnCloseout Jan–Mar
Financial closeout approaching AI: ~$13.3K balance — reallocation modelled
CARTA Open Science Data Hub (COS-DH)
Partner Agreement · no-cost extension to 31 Oct
$40,000
Spend: 61% drawnExtended
Reporting on schedule
AI funding matcher

Calls matched to your work

Scored against faculty expertise, eligibility and past outputs.

Wellcome — Discovery Research94% fit
Closes in 22 days · health systems + AI
Gates Grand Challenges — TB88% fit
Closes in 5 weeks · aligns to DIMA/SynCH work
Active awards11
Total managedR20M+
In pre-award pipeline6
Reports due this quarter3

Pre-award support · AI-assisted, human-approved

Five assisted stages, then a clean handoff to the Research Office system of record. Nothing is submitted in the institution's name without sign-off.

01

Discover

Calls scanned against faculty expertise and scored for fit and eligibility.

AI match
02

Draft

First-draft narrative and budget built from prior outputs and the call text.

AI drafting
03

Evidence

Supporting literature and stats pulled from the corpus, with sources attached.

AI synthesis
04

Critique

A reviewer's-eye pass against the funder's published criteria flags the gaps.

AI review
05

Route

Internal sign-off — HoD, finance, research office — then handoff to submission.

Post-award & closeout · The stage most hubs skip

Awards managed through to clean closeout

Benchmark hubs stop at guidance. This carries each award through contracts, reporting deadlines, milestone sign-off and finance reconciliation — to the closeout the faculty is accountable for.

Stage 1
Discover
Stage 2
Pre-award
Stage 3
Award
Stage 4
Post-award
Stage 5
Closeout
Reporting & milestones Auto-reminders
CB-SITS financial reportCarnegie · Jan–Mar reporting period
Due 14 days
EVAH milestone 2 sign-offTechnical progress · ISC chair approval
Due 30 Jul
COS-DH interim narrativeSubmitted · accepted
Done
Contracts & variationsSigned agreements, amendments, no-cost extensions
3 active
Finance reconciliation — CB-SITS closeout
Awarded budget$181,000
Drawn to date$167,700
Remaining balance$13,300
AI reconciliation modelled a compliant reallocation across budget lines within the 10% overspend provision. Review and confirm before submission.
Closeout packFinal report, asset register, cost recovery, audit trail
Draft ready
Home/Dashboards
The operational workspace · one login, everyone sees their own cut

Sign in once with Wits, get a dashboard shaped to your role

This is the third experience — the authenticated layer. Staff use their existing Wits single sign-on, no new account. The hub holds only operational context against each identity; the academic profile stays in the Visibility Platform. Pick a role to see the difference.

AM Prof. Aletta MillenAssistant Dean: Research · Principal Investigator
Signed in via Wits SSO
Role-based permissions: a PI sees their own grants and supervisees; they can't approve controlled-access requests or reallocate another unit's budget.
Home/Support & development
Postgraduate & researcher development · Delivered through Ulwazi

Training and supervision, not just a course catalogue

The most common feature across benchmarked hubs — here it runs on the university's own approved LMS. Methods courses, research training and live supervision tracking are delivered through Ulwazi, the Wits Canvas-based learning platform already used across the institution.

Methods

Stepped-wedge & cluster trials

Design, power calculation and analysis for pragmatic health-systems evaluations.

62%
Data

POPIA & health data governance

Consent, de-identification and controlled access for human-subjects data.

40%
Writing

Scientific writing & publishing

From first draft to submission, with science-editing support built in.

85%
Grants

Grantsmanship & proposal craft

Funder logic, budgets and narrative — feeding straight into the pre-award portal.

18%
Delivered through Ulwazi · the Wits Canvas-based LMS · institution-wide

Supervision tracker

TM
T. Mokoena — PhDAI triage in PHC facilities
Fieldwork
LN
L. Nkosi — MScTB genomic surveillance
Write-up
AD
A. Dlamini — PhDMaternal NCD linkage
Proposal
RP
R. Patel — MMedPatient continuity & access
Write-up
Milestones & ethics expiry tracked per candidate

Research support directory

The human layer the benchmark hubs do well — surfaced as a directory, federated to the people who actually deliver it.

Science editing

Manuscript editing and language support before submission.

Book a consult →
Biostatistics

Study design, sample size and analysis consults.

Request support →
Evidence synthesis

Systematic reviews and rapid evidence, corpus-assisted.

Start a review →
Research office

Contracts, costing and submission — federated contacts.

Find your officer →
Home/AI & automation
The enabling layer

AI improves the hub — it isn't the point of it

The value is visibility, coordination, access and accountability. AI sits underneath that, doing the heavy reading: better search, matching, metadata, summaries and alerts — so people spend time on judgement, not data entry.

AUTOMATE

Harvest & link

New outputs, grants and deposits auto-ingest, then self-tag and cross-link people, projects and datasets via webhooks.

ENRICH

Metadata & summaries

Draft DataCite-aligned metadata, codebooks and plain-language abstracts generated from uploaded files, ready for review.

MATCH

Funding & collaborators

Calls scored against faculty expertise; partner and reviewer suggestions surfaced from co-authorship and topic graphs.

SYNTHESISE

Evidence on demand

A retrieval assistant grounded in the FHS corpus answers questions and assembles evidence with sources attached.

Human-in-the-loop on everything that touches ethics, compliance, or sensitive data. AI drafts and flags; people approve and submit.